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Related Party Transactions - Additional Information (Detail) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Sep. 30, 2015
Sep. 30, 2014
Dec. 31, 2014
REGENXBIO, Inc [Member]          
Related Party Transaction [Line Items]          
Cash payment to related party $ 1,000,000 $ 2,083,000 $ 2,750,000 $ 5,896,000  
Amounts due to related party 0   0   $ 750,000
University of Pennsylvania [Member]          
Related Party Transaction [Line Items]          
Cash payment to related party 1,000,000 0 4,137,000 0  
Amounts due to related party 21,000   21,000   0
Fidelity Biosciences [Member]          
Related Party Transaction [Line Items]          
Cash payment to related party 0 $ 0 1,000 $ 38,000  
Amounts due to related party $ 0   $ 0   $ 0