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Equity Incentive Plans (Details) - Schedule of restricted stock units - $ / shares
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Schedule of restricted stock units [Abstract]    
Number of Shares, Outstanding beginning 20,798 53,004
Weighted Average Grant Date Fair Value, Outstanding beginning $ 4.99 $ 31.21
Number of Shares, Granted 100,000
Weighted Average Grant Date Fair Value, Granted $ 2.51
Number of Shares, Vested and released (20,420) (131,541)
Weighted Average Grant Date Fair Value, Vested and released $ 3.82 $ 9.68
Number of Shares, Forfeited (378) (665)
Weighted Average Grant Date Fair Value, Forfeited $ 68.02 $ 64.95
Number of Shares, Outstanding ending 20,798
Weighted Average Grant Date Fair Value, Outstanding ending $ 4.99