X0306 4 2019-11-08 0 0001744659 Akero Therapeutics, Inc. AKRO 0001591747 Bitterman Kevin C/O AKERO THERAPEUTICS, INC. 170 HARBOR WAY, 3RD FLOOR SOUTH SAN FRANCISCO CA 94080 1 0 0 0 Stock Option (Right to Buy) 19.97 2019-11-08 4 A 0 26000 0 A 2029-11-07 Common Stock 26000 26000 D This option shall vest and become exercisable in 36 equal monthly installments, commencing on November 8, 2019. This option was granted to the Reporting Person, a director of the Issuer. The proceeds of any sale of shares of common stock issued to the Reporting Person upon exercise of this option will be transferred to Atlas Venture Life Science Advisors, LLC, and as such, the Reporting Person disclaims beneficial ownership of the securities reported herein for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, except to the extent of his pecuniary interest therein, if any. /s/ Kevin Bitterman 2019-11-12