X0306 4 2019-08-19 0 0001326732 Xencor Inc XNCR 0001591313 Desjarlais John R C/O XENCOR, INC. 111 WEST LEMON AVENUE MONROVIA CA 91016 0 1 0 0 Sr. V.P., Research & CSO Common Stock 2019-08-19 4 S 0 35000 40.69 D 56346 D The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.42 to $41.27, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above. Includes the following shares acquired by the Reporting Person pursuant to the Issuer's Employee Stock Purchase Plan: 1,626 shares of Common Stock acquired on December 11, 2018 and 1,622 shares of Common Stock acquired on June 12, 2019. /s/ John R. Desjarlais 2019-08-21