X0306 4 2015-03-17 0 0001326732 Xencor Inc XNCR 0001591313 Desjarlais John R C/O XENCOR, INC. 111 WEST LEMON AVENUE MONROVIA CA 91016 0 1 0 0 Sr. V.P., Research & CSO Common Stock 2015-03-17 4 F 0 10000 15.3518 D 18183 D Sale of shares to cover exercise price and taxes for expiring option. The weighted average sale price for the transaction reported was $15.3518, and the range of prices were between $15.33 and $15.3901. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares purchased or sold at each separate price will be provided. /s/ John J. Kuch, Attorney-in-Fact 2015-03-18