X0306 4 2016-02-04 0001178711 Paratek Pharmaceuticals, Inc. PRTK 0001591113 Radie Robert S C/O PARATEK PHARMACEUTICALS, INC. 75 PARK PLAZA, 4TH FLOOR BOSTON MA 02116 1 0 0 0 Stock Option (right to buy) 14.05 2016-02-04 4 A 0 12000 0 A 2026-02-03 Common Stock 12000 12000 D The exercise price is equal to the closing sales price per share of Common Stock as reported on The Nasdaq Global Market on the date of grant. The shares shall vest as to 1/12 of the shares on the one-month anniversary following February 4, 2016, and on the same calendar date of each successive month thereafter until fully vested, subject to the Reporting Person's continued service to the Company at each vesting date. Remarks: Exhibit List: Exhibit 24 - Power of Attorney /s/ William M. Haskel, Attorney-in-Fact for Robert S. Radie 2016-02-08