Consolidated Statements of Stockholders' Equity - USD ($) shares in Thousands, $ in Thousands	Total	Common Stock [Member]	Additional paid in capital [Member]	Accumulated Other Comprehensive Loss [Member]	Accumulated Deficit [Member]
Balances at Dec. 31, 2020	$ 377,753	$ 4	$ 667,181	$ (360)	$ (289,072)
Balances (Shares) at Dec. 31, 2020		37,476
Issuance of common stock upon public offering, net of transaction costs	216,059		216,059
Issuance of stock, net of transaction costs		4,899
Exercise of stock options	1,292		1,292
Exercise of stock options, Shares		111
Issuance of common stock under employee stock purchase plan	627		627
Issuance of common stock under employee stock purchase plan, shares		19
Stock-based compensation expense	9,920		9,920
Unrealized loss on available-for-sale securities, net	(1,008)			(1,008)
Net loss	(50,139)				(50,139)
Balances at Mar. 31, 2021	554,504	$ 4	895,079	(1,368)	(339,211)
Balances (Shares) at Mar. 31, 2021		42,505
Balances at Dec. 31, 2021	764,298	$ 4	928,095	(2,569)	(161,232)
Balances (Shares) at Dec. 31, 2021		42,831
Vesting of restricted stock units, net of tax	(284)		(284)
Vesting of restricted stock units, Shares		52
Exercise of stock options	337		337
Exercise of stock options, Shares		76
Issuance of common stock under employee stock purchase plan	622		622
Issuance of common stock under employee stock purchase plan, shares		22
Stock-based compensation expense	10,800		10,800
Unrealized loss on available-for-sale securities, net	(9,381)			(9,381)
Net loss	(76,723)				(76,723)
Balances at Mar. 31, 2022	$ 689,669	$ 4	$ 939,570	$ (11,950)	$ (237,955)
Balances (Shares) at Mar. 31, 2022		42,982