Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Current assets
Cash and cash equivalents	$ 191,873	$ 345,209
Marketable securities	202,261	112,230
Accounts receivable, net	27,022	32,439
Prepaid expenses	18,542	18,752
Other current assets	7,179	10,196
Total current assets	446,877	518,826
Marketable securities	370,659	391,907
Accounts receivable, net	2,084	2,262
Property and equipment, net	135,264	131,547
Operating lease right-of-use assets	59,925	60,904
Restricted cash	2,030	2,030
Other assets	8,529	6,428
Total assets	1,025,368	1,113,904
Current liabilities
Accounts payable	24,708	11,387
Accrued expenses and other current liabilities	48,423	76,111
Deferred revenue	3,333	3,333
Operating lease liabilities	2,121	1,752
Liability related to sale of future royalties	41,352	37,889
Total current liabilities	119,937	130,472
Operating lease liabilities	85,568	84,929
Liability related to sale of future royalties	122,514	133,460
Other liabilities	7,680	745
Total liabilities	335,699	349,606
Stockholders’ equity
Preferred stock; $0.0001 par value; 10,000 shares authorized, no shares issued and outstanding at March 31, 2022 and December 31, 2021
Common stock; $0.0001 par value; 100,000 shares authorized at March 31, 2022 and December 31, 2021; 42,982 and 42,831 shares issued and outstanding at March 31, 2022 and December 31, 2021, respectively	4	4
Additional paid-in capital	939,570	928,095
Accumulated other comprehensive loss	(11,950)	(2,569)
Accumulated deficit	(237,955)	(161,232)
Total stockholders’ equity	689,669	764,298
Total liabilities and stockholders’ equity	$ 1,025,368	$ 1,113,904