Supplemental Disclosures - Schedules of Accrued Expenses and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Payables And Accruals [Abstract]
Accrued sublicense fees and royalties	$ 23,483	$ 12,160
Accrued personnel costs	19,849	13,155
Accrued external research and development expenses	11,783	9,738
Accrued income taxes payable	11,325	3,135
Accrued purchases of property and equipment	5,285	7,853
Accrued external general and administrative expenses	3,642	2,865
Other accrued expenses and current liabilities	744	176
Accrued expenses and other current liabilities	$ 76,111	$ 49,082