License and Collaboration Agreements - Summary of Changes in Balances of Receivables, Contract Assets and Deferred Revenue (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Accounts receivable, net, current and non-current:
Balance, beginning of period	$ 46,266	$ 42,303	$ 31,599
Additions	472,347	158,682	39,203
Deductions	(483,912)	(154,719)	(28,499)
Balance, end of period	34,701	46,266	42,303
Contract assets:
Balance, beginning of period	350		750
Additions	1,074	350	1,000
Deductions	(350)		(1,750)
Balance, end of period	1,074	350
Deferred revenue, current and non-current:
Balance, beginning of period	4,232	3,333	3,933
Additions		1,124
Deductions	(899)	(225)	(600)
Balance, end of period	3,333	4,232	3,333
Revenue recognized during the period from:
Amounts included in deferred revenue at beginning of period	390		600
Performance obligations satisfied in previous periods	$ 98,575	$ 146,772	$ 26,689