Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets
Cash and cash equivalents	$ 345,209	$ 338,426
Marketable securities	112,230	137,314
Accounts receivable (net of allowance of $7,678 as of December 31, 2020)	32,439	42,999
Prepaid expenses	18,752	10,505
Other current assets	10,196	1,953
Total current assets	518,826	531,197
Marketable securities	391,907	46,809
Accounts receivable (net of allowance of $3,758 as of December 31, 2021)	2,262	3,267
Property and equipment, net	131,547	56,467
Operating lease right-of-use assets	60,904	63,815
Restricted cash	2,030	1,330
Other assets	6,428	5,279
Total assets	1,113,904	708,164
Current liabilities
Accounts payable	11,387	10,622
Accrued expenses and other current liabilities	76,111	49,082
Deferred revenue	3,333	449
Operating lease liabilities	1,752	2,500
Liability related to sale of future royalties	37,889	18,794
Total current liabilities	130,472	81,447
Deferred revenue		3,783
Operating lease liabilities	84,929	70,153
Liability related to sale of future royalties	133,460	174,504
Other liabilities	745	524
Total liabilities	349,606	330,411
Commitments and contingencies (Note 8)
Stockholders’ equity
Preferred stock; $0.0001 par value; 10,000 shares authorized, no shares issued and outstanding at December 31, 2021 and 2020
Common stock; $0.0001 par value; 100,000 shares authorized at December 31, 2021 and 2020; 42,831 and 37,476 shares issued and outstanding at December 31, 2021 and 2020, respectively	4	4
Additional paid-in capital	928,095	667,181
Accumulated other comprehensive loss	(2,569)	(360)
Accumulated deficit	(161,232)	(289,072)
Total stockholders’ equity	764,298	377,753
Total liabilities and stockholders’ equity	$ 1,113,904	$ 708,164