Consolidated Statements of Operations and Comprehensive Income (Loss) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Revenues
Revenues	$ 30,773	$ 98,912	$ 71,692	$ 133,122
Operating Expenses
Cost of revenues	14,105	17,364	28,775	25,457
Research and development	47,855	43,968	133,459	119,114
General and administrative	21,030	15,859	57,293	46,246
Provision for credit losses and other	5,131	7,770	5,781	7,887
Total operating expenses	88,121	84,961	225,308	198,704
Income (loss) from operations	(57,348)	13,951	(153,616)	(65,582)
Other Income (Expense)	(58,435)	8,304	(167,108)	(64,951)
Interest income from licensing	117	1,444	700	4,141
Investment income (loss)	5,535	(6,607)	6,514	(4,071)
Interest expense	(6,709)		(19,777)
Total other income (expense)	(1,057)	(5,163)	(12,563)	70
Income (loss) before income taxes	(58,405)	8,788	(166,179)	(65,512)
Income Tax Benefit (Expense)		3	(4)	503
Net income (loss)	(58,405)	8,791	(166,183)	(65,009)
Other Comprehensive Income (Loss)
Unrealized gain (loss) on available-for-sale securities, net	(30)	(487)	(925)	58
Total other comprehensive income (loss)	(30)	(487)	(925)	58
Comprehensive income (loss)	$ (58,435)	$ 8,304	$ (167,108)	$ (64,951)
Net income (loss) per share:
Basic	$ (1.37)	$ 0.24	$ (3.93)	$ (1.75)
Diluted	$ (1.37)	$ 0.23	$ (3.93)	$ (1.75)
Weighted-average common shares outstanding:
Basic	42,629	37,342	42,324	37,234
Diluted	42,629	38,877	42,324	37,234
License and royalty [Member]
Revenues
Revenues	$ 30,773	$ 98,912	$ 71,692	$ 133,122