Liability Related to Sale of Future Royalties - Additional Information (Details) $ in Thousands	3 Months Ended
	Mar. 31, 2021 USD ($)
Liability Related To Sale Of Future Royalties [Line Items]
Repurchase of call option amount	$ 300,000
November 7, 2024
Liability Related To Sale Of Future Royalties [Line Items]
Repurchase of call option amount, befor exercised	1,000
Royalty Purchase Agreement [Member]
Liability Related To Sale Of Future Royalties [Line Items]
Non-cash interest expense	6,702
H C R [Member]
Liability Related To Sale Of Future Royalties [Line Items]
Proceeds from Royalties Received	4,000
Deferred Transaction Cost	3,500
Non-cash interest expense	$ 192,500
Interest Rate, Effective Percentage	13.90%
H C R [Member] | Other Noncurrent Liabilities
Liability Related To Sale Of Future Royalties [Line Items]
Proceeds from sale of future royalties	$ 196,000
H C R [Member] | November 7, 2024
Liability Related To Sale Of Future Royalties [Line Items]
Royalty Payment Cap Amount	260,000
H C R [Member] | November 8, 2024
Liability Related To Sale Of Future Royalties [Line Items]
Royalty Payment Cap Amount	300,000
H C R [Member] | Royalty Purchase Agreement [Member]
Liability Related To Sale Of Future Royalties [Line Items]
Purchase Agreement	$ 200,000