Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2021	Dec. 31, 2020
Current assets
Cash and cash equivalents	$ 291,482	$ 338,426
Marketable securities	149,398	137,314
Accounts receivable, net	41,039	42,999
Prepaid expenses	13,839	10,505
Other current assets	2,880	1,953
Total current assets	498,638	531,197
Marketable securities	215,598	46,809
Accounts receivable, net	2,859	3,267
Property and equipment, net	89,342	56,467
Operating lease right-of-use assets	62,607	63,815
Restricted cash	1,330	1,330
Other assets	9,068	5,279
Total assets	879,442	708,164
Current liabilities
Accounts payable	11,311	10,622
Accrued expenses and other current liabilities	41,605	49,082
Deferred revenue	395	449
Operating lease liabilities	1,843	2,500
Liability related to sale of future royalties	28,807	18,794
Total current liabilities	83,961	81,447
Deferred revenue	3,729	3,783
Operating lease liabilities	75,078	70,153
Liability related to sale of future royalties	161,722	174,504
Other liabilities	448	524
Total liabilities	324,938	330,411
Stockholders’ equity
Preferred stock; $0.0001 par value; 10,000 shares authorized, and no shares issued and outstanding at March 31, 2021 and December 31, 2020
Common stock; $0.0001 par value; 100,000 shares authorized at March 31, 2020 and December 31, 2019; 37,190 and 36,992 shares issued and outstanding at March 31, 2020 and December 31, 2019, respectively	4	4
Additional paid-in capital	895,079	667,181
Accumulated other comprehensive loss	(1,368)	(360)
Accumulated deficit	(339,211)	(289,072)
Total stockholders’ equity	554,504	377,753
Total liabilities and stockholders’ equity	$ 879,442	$ 708,164