Commitments and Contingencies (Tables)

12 Months Ended

Dec. 31, 2016

Schedule of Future Minimum Lease Payments Under Non-Cancelable Operating Leases

As of December 31, 2016, future minimum lease payments under non-cancelable operating leases are as follows (in thousands):

	Operating
	Leases
2017	$	1,589
2018		1,637
2019		1,685
2020		1,603
2021		664
Thereafter		950
Total minimum lease payments	$	8,128

The Trustees of the University of Pennsylvania [Member]

Summary of Expenses Incurred by Company

Expenses incurred by the Company related to its license from Penn were as follows:

	Years Ended December 31,
	2016		2015		2014
Sublicense fees	$	430	$	703	$	443
Royalties on sales of reagents		11		9		17
Maintenance of licensed patents		133		154		256
	$	574	$	866	$	716

GlaxoSmithKline LLC [Member]

Summary of Expenses Incurred by Company

Expenses incurred by the Company related to its license from GSK were as follows:

	Years Ended December 31,
	2016		2015		2014
Sublicense fees	$	430	$	703	$	443
Royalties on sales of reagents		7		5		10
Maintenance of licensed patents		597		573		432
	$	1,034	$	1,281	$	885