Related Party Transactions (Tables)

12 Months Ended

Dec. 31, 2015

The Trustees of the University of Pennsylvania [Member]

Summary of Expenses Incurred for Manufacturing and Research and Development

Expenses incurred by the Company for manufacturing and research and development for the nine months ended September 30, 2015 and the years ended December 31, 2014 and 2013 are as follows:

	Nine Months Ended		Years Ended
	September 30,		December 31,
	2015		2014		2013
Manufacturing of reagents for sale	$	80	$	92	$	143
Research and development services		5,136		1,286		2,778
	$	5,216	$	1,378	$	2,921

Summary of Expenses Incurred by Company

Expenses incurred by the Company related to its license from Penn were as follows:

	Years Ended December 31,
	2015		2014		2013
Sublicense fees	$	703	$	443	$	76
Royalties on sales of reagents		9		17		18
Maintenance of licensed patents		154		256		120
	$	866	$	716	$	214

FoxKiser,LLP [Member]

Summary of Expenses Incurred by Company

Costs incurred by the Company under the services agreement with FoxKiser were as follows:

	Years Ended December 31,
	2015		2014		2013
Research and development	$	168	$	1,283	$	1,111
General and administrative		237		1,696		1,469
	$	405	$	2,979	$	2,580