Consolidated Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024
Cash flows from operating activities
Net income (loss)	$ 6,083	$ (63,330)
Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities
Stock-based compensation expense	8,537	9,602
Depreciation and amortization	3,955	4,180
Net accretion of discounts on marketable debt securities	(1,071)	(468)
Impairment of long-lived assets		2,101
Non-cash interest expense	(277)	688
Other non-cash adjustments	(10)	(71)
Changes in operating assets and liabilities
Accounts receivable	1,572	9,177
Prepaid expenses	(2,027)	930
Other current assets	(2,240)	(6,826)
Operating lease right-of-use assets	1,638	1,528
Other assets	1,013	590
Accounts payable	(3,651)	8,461
Accrued expenses and other current liabilities	(14,489)	(17,077)
Deferred revenue	39,770	(135)
Operating lease liabilities	(2,219)	(2,041)
Other liabilities	(2,955)	(2,764)
Net cash provided by (used in) operating activities	33,629	(55,455)
Cash flows from investing activities
Purchases of marketable debt securities	(19,157)	(55,190)
Maturities of marketable debt securities	64,924	68,930
Purchases of property and equipment	(1,024)	(557)
Net cash provided by investing activities	44,743	13,183
Cash flows from financing activities
Proceeds from exercise of stock options	150	884
Taxes paid related to net settlement of stock-based awards	(510)	(910)
Proceeds from issuance of common stock under employee stock purchase plan	307	411
Proceeds from public offering of common stock and pre-funded warrants, net of issuance costs		131,601
Offering expenses related to at-the-market offering program	(147)	(35)
Repayments under liability related to sale of future royalties, net of imputed interest	(5,594)	(11,226)
Net cash provided by (used in) financing activities	(5,794)	120,725
Net increase in cash and cash equivalents and restricted cash	72,578	78,453
Cash and cash equivalents and restricted cash
Beginning of period	59,556	36,552
End of period	$ 132,134	$ 115,005