Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Revenues
Revenues	$ 22,295	$ 19,977	$ 37,917	$ 39,115
Operating Expenses
Cost of revenues	10,579	9,475	14,862	13,587
Research and development	48,869	59,886	103,713	118,402
General and administrative	18,855	23,698	37,146	46,332
Impairment of long-lived assets			2,101
Other operating expenses (income)	29	26	(5)	59
Total operating expenses	78,332	93,085	157,817	178,380
Loss from operations	(56,037)	(73,108)	(119,900)	(139,265)
Other Income (Expense)
Interest income from licensing	29	40	66	110
Investment income	3,468	2,127	5,937	4,293
Interest expense	(449)	(1,120)	(2,422)	(3,875)
Total other income	3,048	1,047	3,581	528
Net loss	(52,989)	(72,061)	(116,319)	(138,737)
Other Comprehensive Income
Unrealized gain on available-for-sale securities, net	963	1,524	2,163	5,303
Total other comprehensive income	963	1,524	2,163	5,303
Comprehensive loss	$ (52,026)	$ (70,537)	$ (114,156)	$ (133,434)
Net loss per share, basic	$ (1.05)	$ (1.66)	$ (2.41)	$ (3.19)
Net loss per share, diluted	$ (1.05)	$ (1.66)	$ (2.41)	$ (3.19)
Weighted-average common shares outstanding, basic	50,601	43,531	48,167	43,491
Weighted-average common shares outstanding, diluted	50,601	43,531	48,167	43,491
License and royalty [Member]
Revenues
Revenues	$ 22,295	$ 19,977	$ 37,917	$ 39,115