Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Current assets
Cash and cash equivalents	$ 70,091	$ 96,952
Marketable securities	261,726	267,690
Accounts receivable	18,861	28,082
Prepaid expenses	15,521	13,900
Other current assets	23,003	9,352
Total current assets	389,202	415,976
Marketable securities	141,709	200,560
Accounts receivable, net	1,300	1,504
Property and equipment, net	141,573	141,685
Operating lease right-of-use assets	63,726	65,116
Restricted cash	2,030	2,030
Other assets	8,290	6,397
Total assets	747,830	833,268
Current liabilities
Accounts payable	23,283	27,213
Accrued expenses and other current liabilities	31,709	46,794
Deferred revenue	1,311	1,829
Operating lease liabilities	6,303	5,997
Liability related to sale of future royalties	49,728	48,601
Total current liabilities	112,334	130,434
Operating lease liabilities	86,992	88,802
Liability related to sale of future royalties	77,382	89,005
Other liabilities	5,983	8,832
Total liabilities	282,691	317,073
Stockholders’ equity
Preferred stock; $0.0001 par value; 10,000 shares authorized, no shares issued and outstanding at March 31, 2023 and December 31, 2022
Common stock; $0.0001 par value; 100,000 shares authorized at March 31, 2023 and December 31, 2022; 43,465 and 43,299 shares issued and outstanding at March 31, 2023 and December 31, 2022, respectively	4	4
Additional paid-in capital	984,986	973,145
Accumulated other comprehensive loss	(11,622)	(15,401)
Accumulated deficit	(508,229)	(441,553)
Total stockholders’ equity	465,139	516,195
Total liabilities and stockholders’ equity	$ 747,830	$ 833,268