Supplemental Disclosures - Schedules of Accrued Expenses and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Payables and Accruals [Abstract]
Accrued sublicense fees and royalties	$ 15,768	$ 23,483
Accrued personnel costs	18,071	19,849
Accrued external research and development expenses	9,216	11,783
Accrued income taxes payable		11,325
Accrued purchases of property and equipment	806	5,285
Accrued external general and administrative expenses	2,187	3,642
Other accrued expenses and current liabilities	746	744
Accrued expenses and other current liabilities	$ 46,794	$ 76,111