License and Collaboration Agreements - Schedule Of License and Royalty Revenue (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Other license and royalty revenue	$ 10,805	$ 5,369	$ 12,936
Total license and royalty revenue	112,724	470,347	154,567
Abb Vie Collaboration And License Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Royalties on net sales of Zolgensma		370,000
Zolgensma Royalties [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Royalties on net sales of Zolgensma	$ 101,919	$ 94,978	61,631
Achievement Of Sales Based Milestone For Zolgensma [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Royalties on net sales of Zolgensma			$ 80,000