Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Current assets
Cash and cash equivalents	$ 96,952	$ 345,209
Marketable securities	267,690	112,230
Accounts receivable	28,082	32,439
Prepaid expenses	13,900	18,752
Other current assets	9,352	10,196
Total current assets	415,976	518,826
Marketable securities	200,560	391,907
Accounts receivable (net of allowance of $4,152 and $3,758 as of December 31, 2022 and 2021, respectively)	1,504	2,262
Property and equipment, net	141,685	131,547
Operating lease right-of-use assets	65,116	60,904
Restricted cash	2,030	2,030
Other assets	6,397	6,428
Total assets	833,268	1,113,904
Current liabilities
Accounts payable	27,213	11,387
Accrued expenses and other current liabilities	46,794	76,111
Deferred revenue	1,829	3,333
Operating lease liabilities	5,997	1,752
Liability related to sale of future royalties	48,601	37,889
Total current liabilities	130,434	130,472
Operating lease liabilities	88,802	84,929
Liability related to sale of future royalties	89,005	133,460
Other liabilities	8,832	745
Total liabilities	317,073	349,606
Commitments and contingencies (Note 8)
Stockholders’ equity
Preferred stock; $0.0001 par value; 10,000 shares authorized, no shares issued and outstanding at December 31, 2022 and 2021
Common stock; $0.0001 par value; 100,000 shares authorized at December 31, 2022 and 2021; 43,299 and 42,831 shares issued and outstanding at December 31, 2022 and 2021, respectively	4	4
Additional paid-in capital	973,145	928,095
Accumulated other comprehensive loss	(15,401)	(2,569)
Accumulated deficit	(441,553)	(161,232)
Total stockholders’ equity	516,195	764,298
Total liabilities and stockholders’ equity	$ 833,268	$ 1,113,904