CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022
Cash flows from operating activities:
Net loss	$ (170,874)	$ (84,089)
Adjustments to reconcile net loss to net cash used in operating activities:
Share-based compensation expense	41,124	14,487
Issuance of common stock under license agreement	5,693	0
Non-cash interest expense and amortization of debt issuance costs	194	100
Depreciation and amortization	372	159
Accretion and amortization of premiums and discounts on available-for-sale securities	(8,423)	727
Non-cash lease expense	59	40
Net loss on extinguishment of debt	181	0
Fees paid directly to creditor related to extinguishment of debt	514	0
Amortization of issuance costs, 2021 ATM	0	75
Other non-cash items	31	0
Changes in operating assets and liabilities:
Prepaid expenses and other assets	(4,489)	(2,622)
Unbilled revenue - related party	0	52
Deferred revenue - related party	(216)	(216)
Accounts payable	(10,524)	9,779
Accrued and other liabilities	188	1,712
Net cash used in operating activities	(146,170)	(59,796)
Cash flows from investing activities:
Purchases of short-term investments	(135,385)	(5,192)
Proceeds from sales and maturities of short-term investments	211,694	71,235
Purchase of property and equipment, net	(850)	(566)
Net cash provided by investing activities	75,459	65,477
Cash flows from financing activities:
Proceeds from the issuance of common stock, pursuant to 2022 Public Offering	0	266,788
Proceeds from the issuance of Series B preferred stock	0	44,000
Proceeds from issuance of long-term debt, net of costs	15,000	4,554
Payment of debt extinguishment costs	(514)	0
Proceeds from the sale of common stock - warrants	1,881	935
Proceeds from issuance of common stock upon the exercise of stock options	9,782	908
Proceeds from the issuance of common stock for cash under employee stock purchase plan	580	183
Net cash provided by financing activities	26,729	296,230
Net (decrease) increase in cash and cash equivalents	(43,982)	301,911
Cash and cash equivalents at beginning of period	155,579	42,299
Cash and cash equivalents at end of period	111,597	344,210
Supplemental disclosure of cash flow information
Cash paid for interest	434	144
Supplemental disclosure of non-cash investing and financing activities
Unpaid common and preferred stock issuance costs included in accrued liabilities	0	39
Purchases of property and equipment in accounts payable	25	44
Extinguishment of long-term debt	4,707	0
Issuance of long-term debt	5,000	0
Common Stock
Cash flows from financing activities:
Payment of issuance costs	0	(18,146)
Preferred Stock
Cash flows from financing activities:
Payment of issuance costs	$ 0	$ (2,992)