CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Cash flows from operating activities:
Net loss	$ (129,874)	$ (79,413)
Adjustments to reconcile net loss to net cash (used in) operating activities:
Issuance of common stock under license agreement	0	7,500
Share-based compensation expense	19,765	14,465
Non-cash interest expense and amortization of debt issuance costs	228	87
Depreciation and amortization	255	120
Accretion and amortization of premiums and discounts on available-for-sale securities	(210)	965
Realized gain on investments	0	(4)
Loss on sale of equipment	0	77
Non-cash lease expenses	36	(102)
Changes in operating assets and liabilities:
Prepaid expenses and other assets	(3,339)	(1,496)
Accounts payable	11,524	1,655
Accrued and other liabilities	7,716	1,380
Unbilled revenue	349	(451)
Deferred revenue	(288)	636
Net cash used in operating activities	(93,838)	(54,581)
Cash flows from investing activities:
Purchases of short-term investments	(223,264)	(188,431)
Proceeds from sales and maturities of short-term investments	108,935	114,398
Proceeds from sale of property and equipment	0	79
Purchases of property and equipment	(797)	(338)
Net cash used in investing activities	(115,126)	(74,292)
Cash flows from financing activities:
Proceeds from the issuance of common stock, pursuant to 2022 and 2021 Public Offering and September 2022 and April 2021 ATM Agreement	291,874	114,242
Proceeds from the issuance of Series B preferred stock	44,000	16,960
Proceeds from the exercise of warrants	935	1,285
Proceeds from issuance of long-term debt	5,000	0
Payment of debt issuance costs	(446)	0
Proceeds from issuance of common stock upon the exercise of stock options	2,762	1,027
Proceeds from the issuance of common stock for cash under employee stock purchase plan	183	39
Net cash provided by financing activities	322,244	125,275
Net increase (decrease) in cash and cash equivalents	113,280	(3,598)
Cash and cash equivalents at beginning of period	42,299	45,897
Cash and cash equivalents at end of period	155,579	42,299
Supplemental disclosure of cash flow information
Interest paid	293	0
Supplemental disclosure of non-cash investing and financing activities
Purchase of property and equipment in accounts payable and accrued liabilities	380	4
Amortization of public offering costs	75	87
Common Stock
Cash flows from financing activities:
Payment of issuance costs	(19,072)	(6,987)
Preferred Stock
Cash flows from financing activities:
Payment of issuance costs	$ (2,992)	$ (1,291)