X0306 4 2018-08-21 0 0001590750 MIRAGEN THERAPEUTICS, INC. MGEN 0001693134 Levy Adam Scott C/O MIRAGEN THERAPEUTICS, INC. 6200 LOOKOUT ROAD BOULDER CO 80301 0 1 0 0 Chief Business Officer Common Stock 13040 D Includes 1,250 shares acquired under the Miragen Therapeutics, Inc. 2016 Employee Stock Purchase Plan on August 21, 2018. /s/ Brent D. Fassett, as Attorney-in-Fact for Adam S. Levy 2018-08-22