144 0001536290 XXXXXXXX LIVE 0001590560 uniQure N.V. 001-36294 PAASHEUVELWEG 25A AMSTERDAM P7 1105 BP 1-339-970-7000 Kapusta Matthew C Officer Director CEO AND MANAGING DIRECTOR ORDINARY SHARES CITIGROUP GLOBAL MARKETS

390 GREENWICH ST NEW YORK NY 10013

41671 1932516.25 63067485 06/18/2026 NASDAQ ORDINARY SHARES 06/18/2026 Vested Stock from PSU and RSU UNIQURE NV N 37015 06/18/2026 COMPENSATION Ordinary Shares 06/18/2026 Stock option exercise and sale UNIQURE NV N 4656 06/18/2026 Cash N Kapusta Matthew C

PAASHEUVELWEG 25A AMSTERDAM P7 1105BP

ORDINARY SHARES 06/17/2026 152844 6724136.05 Kapusta Matthew C

PAASHEUVELWEG 25A AMSTERDAM P7 1105BP

ORDINARY SHARES 06/18/2026 11585 563610.25 Shares sold were from vested positions resulting from PSU and RSU activity. Options were exercised and sold as well from established 10b51 plan adopted in October 2025. Under securities to be sold the acquired range was various dates 06/18/2026 10/05/2025 CONFORMED SIGNATURE ON FILE