144 0001376099 XXXXXXXX LIVE 0001590560 uniQure N.V. 001-36294 PAASHEUVELWEG 25A AMSTERDAM P7 1105 BP 1-339-970-7000 Kaye Jack Director Ordinary Shares Citigroup Global Markets, Inc

390 Greenwich Street New York NY 10013

5295 225393.40 63067485 06/17/2026 NASDAQ Ordinary Shares 06/17/2026 Stock option exercise pursuant to 10b51 plan UniQure N.A. N 5295 06/17/2026 cash N Jack Kaye

paasheuvelweg 25 a Amsterdam P7 1105BP

Ordinary Shares 06/03/2026 2645 79384.35 Jack Kaye

paasheuvelweg 25 a, AMSTERDAM P7 1105BP

Ordinary shares 06/11/2026 1993 53938.39 Shares being sold are pursuant to the 10b51 plan adopted June 2025 06/17/2026 06/16/2025 Conformed Signature on File