144 0001536290 XXXXXXXX LIVE 0001590560 uniQure N.V. 001-36294 PAASHEUVELWEG 25A AMSTERDAM P7 1105 BP 1-339-970-7000 Kapusta Matthew C Director ORDINARY SHARES CITIGROUP GLOBAL MARKETS

390 GREENWICH ST NEW YORK NY 10013

14581 132165.10 62291663 03/04/2026 NASDAQ ORDINARY SHARES 03/04/2026 RESTRICTED STOCK UNITS VESTING UNIQURE NV N 33000 03/04/2026 COMPENSATION N MATTHEW KAPUSTA

PAASHEUVELWEG 25A AMSTERDAM P7 1105BP

ORDINARY SHARES 02/25/2026 12378 295306.90 MATTHEW KAPUSTA

PAASHEUVELWEG 25A AMSTERDAM P7 1105BP

ORDINARY SHARES 03/02/2026 34437 342586.16 UNDER SECURITIES TO BE SOLD DATE ACQUIRED WAS VARIOUS DATES. THESE SELL TO COVER TRANSACTIONS WERE THE RESULT OF THE VESTING AND SETTLEMENT OF EQUITY AWARDS. THEY WERE NON DISCRETIONARY TRANSACTIONS 03/04/2026 CONFORMED SIGNATURE ON FILE