CONSOLIDATED BALANCE SHEETS (Parenthetical) $ in Thousands	Sep. 30, 2022 USD ($) shares	Sep. 30, 2022 € / shares	Dec. 31, 2021 USD ($) shares	Dec. 31, 2021 € / shares
Accumulated depreciation | $	$ 40,500		$ 36,900
Intangible assets, net | $	$ 53,837		$ 62,686
Ordinary shares, par value (in euros per share) | € / shares		€ 0.05		€ 0.05
Ordinary shares, authorized | shares	80,000,000		80,000,000
Ordinary shares, issued | shares	46,815,109		46,298,635
Ordinary shares, outstanding | shares	46,815,109		46,298,635
In-process research & development
Intangible assets, net | $	$ 52,500		$ 60,800