Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

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Share-based compensation - Summary of share-based compensation expense and unrecognized costs (Details) - 2014 Plan - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019	Jun. 30, 2020	Jun. 30, 2019	Dec. 31, 2019	Jun. 30, 2018
Share-based compensation
Authorized shares					3,000,000	8,601,471
Share-based compensation expense	$ 5,714	$ 4,576	$ 10,054	$ 8,854
Unrecognized compensation costs	46,674		$ 46,674
Weighted-average remaining period for recognition (in years)			2 years 7 months 17 days
Research and development expenses
Share-based compensation
Share-based compensation expense	2,889	2,119	$ 5,271	4,099
Selling, general and administrative expense
Share-based compensation
Share-based compensation expense	2,825	2,457	4,783	4,755
Share options
Share-based compensation
Share-based compensation expense	$ 2,746	2,004	$ 4,954	4,080
Outstanding of fully vested share options	2,879,733		2,879,733		2,683,104
Unrecognized compensation costs	$ 27,450		$ 27,450
Weighted-average remaining period for recognition (in years)			3 years
Restricted share units ("RSUs")
Share-based compensation
Share-based compensation expense	2,209	995	$ 3,653	1,925
Unrecognized compensation costs	15,705		$ 15,705
Weighted-average remaining period for recognition (in years)			2 years 3 months 10 days
Performance share units ("PSUs")
Share-based compensation
Share-based compensation expense	759	$ 1,577	$ 1,447	$ 2,849
Unrecognized compensation costs	$ 3,519		$ 3,519
Weighted-average remaining period for recognition (in years)			1 year 4 months 13 days