CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Mar. 31, 2020	Dec. 31, 2019
Current assets
Cash and cash equivalents	$ 342,029	$ 377,793
Accounts receivable and accrued income from related party	258	947
Prepaid expenses	5,738	4,718
Other current assets	1,576	748
Total current assets	349,601	384,206
Non-current assets
Property, plant and equipment, net of accumulated depreciation of $29.8 million as of March 31, 2020 and $28.6 million as of December 31, 2019 respectively	27,736	28,771
Operating lease right-of-use assets	26,288	26,797
Intangible assets, net	7,211	5,427
Goodwill	486	496
Restricted cash	2,921	2,933
Total non-current assets	64,642	64,424
Total assets	414,243	448,630
Current liabilities
Accounts payable	4,989	5,681
Accrued expenses and other current liabilities	9,507	12,457
Current portion of operating lease liabilities	5,900	5,865
Current portion of deferred revenue	6,732	7,627
Total current liabilities	27,128	31,630
Non-current liabilities
Long-term debt	36,209	36,062
Operating lease liabilities, net of current portion	30,518	31,133
Deferred revenue, net of current portion	23,713	23,138
Derivative financial instruments related party	1,004	3,075
Other non-current liabilities	524	534
Total non-current liabilities	91,968	93,942
Total liabilities	119,096	125,572
Commitments and contingencies
Shareholders' equity
Ordinary shares, 0.05 par value: 60,000,000 shares authorized at March 31, 2020 and December 31, 2019 and 44,299,596 and 43,711,954 ordinary shares issued and outstanding at March 31, 2020 and December 31, 2019, respectively.	2,683	2,651
Additional paid-in-capital	992,136	986,803
Accumulated other comprehensive loss	(11,966)	(6,689)
Accumulated deficit	(687,706)	(659,707)
Total shareholders' equity	295,147	323,058
Total liabilities and shareholders' equity	$ 414,243	$ 448,630