CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017
Cash flows from operating activities
Net loss	$ (61,416)	$ (51,786)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation, amortization and impairment losses	10,447	6,036
Share-based compensation expense	7,352	5,978
Change in fair value of derivative financial instruments and contingent consideration	(3,516)	2,704
Unrealized foreign exchange (gains) / losses	(4,210)	1,821
Change in deferred taxes	237
Change in lease incentives	(284)	1,938
Changes in operating assets and liabilities:
Accounts receivable and accrued income, prepaid expenses and other current assets	768	9,477
Accounts payable	1,289	(1,440)
Accrued expenses and other liabilities	(1,559)	(1,331)
Deferred revenue	(7,142)	(19,620)
Net cash used in operating activities	(58,034)	(46,223)
Cash flows from investing activities
Purchase of intangible assets	(1,698)	(1,124)
Purchase of property, plant and equipment	(1,805)	(3,244)
Net cash used in investing activities	(3,503)	(4,368)
Cash flows from financing activities
Proceeds from issuance of shares related to employee stock option plans	4,637	1,036
Proceeds from pubic offering of shares, net of issuance costs	138,480
Net cash generated from financing activities	143,117	1,036
Currency effect cash, cash equivalents and restricted cash	(1,431)	6,634
Net increase (decrease) in cash, cash equivalents and restricted cash	80,149	(42,921)
Cash, cash equivalents and restricted cash at beginning of period	161,851	134,324
Cash, cash equivalents and restricted cash at the end of period	242,000	91,403
Supplemental cash flow disclosures:
Total cash, cash equivalents and restricted cash	161,851	134,324
Cash paid for interest	(1,498)	(1,130)
Non-cash increases / (decreases) in accounts payables related to purchases of intangible assets and property, plant and equipment	$ 12	$ (1,635)