CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY - 9 months ended Sep. 30, 2018 - USD ($) $ in Thousands	Ordinary shares	Additional paid-in capital	Accumulated other comprehensive income/(loss)	Accumulated deficit	Total
Beginning balance at Dec. 31, 2017	$ 1,947	$ 566,530	$ (3,800)	$ (475,318)	$ 89,359
Beginning balance (in shares) at Dec. 31, 2017	31,339,040				31,339,040
Increase (decrease) in shareholders' equity
Cumulative effect of retroactive implementation of ASC 606 Revenue recognition			1,802	23,116	$ 24,918
Loss for the period				(61,416)	(61,416)
Other comprehensive loss			(3,489)		(3,489)
Follow-on public offering	$ 309	138,182			138,491
Follow-on public offering (in shares)	5,175,000
Exercise of share options	$ 18	4,619			4,637
Exercise of share options (in shares)	416,211
Restricted share units distributed during the period	$ 20	(20)
Restricted share units distributed during the period (in shares)	344,948
Share-based compensation expense		7,352			7,352
Ending balance at Sep. 30, 2018	$ 2,294	$ 716,663	$ (5,487)	$ (513,618)	$ 199,852
Ending balance (in shares) at Sep. 30, 2018	37,275,199				37,275,199