Property, plant and equipment (Tables)

9 Months Ended

Sep. 30, 2018

Property, plant and equipment

Schedule of property, plant and equipment

	September 30,		December 31,
	2018		2017
	in thousands
Leasehold improvements	$	32,328	$	32,297
Laboratory equipment		16,598		15,976
Office equipment		2,273		2,304
Construction-in-progress		901		745
Total property, plant, and equipment		52,100		51,322
Less accumulated depreciation		(21,298)		(17,041)
Property, plant and equipment, net	$	30,802	$	34,281