Collaboration arrangements and concentration of credit risk (Tables)

9 Months Ended

Sep. 30, 2018

Collaboration arrangements and concentration of credit risk

Schedule of collaboration and license revenue

	Three months ended September 30,				Nine months ended September 30,
	2018		2017		2018		2017
	in thousands
Bristol Myers Squibb	$	3,148	$	2,260	$	9,676	$	5,877
Chiesi Farmaceutici S.p.A (terminated in 2017)		—		—		—		4,646
Total	$	3,148	$	2,260	$	9,676	$	10,523

Schedule of amounts owed in relation to collaboration

	September 30,		December 31,
	2018		2017
	in thousands
Bristol Myers Squibb	$	552	$	1,586