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Fair value measurement - Changes in Level 3 Liabilities and Contingent Consideration (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2018
Dec. 31, 2017
Dec. 31, 2014
Changes in Level 3 liabilities      
Beginning Balance $ 1,600    
Ending Balance $ 1,000 $ 1,600  
Contingent consideration      
Company's weighted average rate of capital 12.00% 12.00%  
Fair value of derivative financial instruments $ 1,600 $ 1,600  
InoCard      
Contingent consideration      
Percentage of future milestones that can be settled with ordinary shares     50.00%
Level 3      
Changes in Level 3 liabilities      
Beginning Balance 5,599    
(Gains) / losses recognized in profit or loss (756)    
Currency translation effects 151    
Ending Balance 4,994 5,599  
Contingent consideration      
Fair value of derivative financial instruments 5,599 5,599  
Level 3 | Contingent consideration      
Changes in Level 3 liabilities      
Beginning Balance 3,964    
(Gains) / losses recognized in profit or loss (54)    
Currency translation effects 110    
Ending Balance 4,020 3,964  
Contingent consideration      
Fair value of derivative financial instruments 3,964 3,964  
Level 3 | Derivative financial instruments      
Changes in Level 3 liabilities      
Beginning Balance 1,635    
(Gains) / losses recognized in profit or loss (702)    
Currency translation effects 41    
Ending Balance $ 974 1,635  
Contingent consideration      
Moving out of all milestones, in months 6 months    
Increasing the POS for the first milestone 20.00%    
Decreasing the POS for the first milestone 20.00%    
Discount rate 12.00%    
Reduced discount rate 2.00%    
Increased discount rate 22.00%    
Fair value of derivative financial instruments $ 1,635 $ 1,635  
Moving out of all milestones by 6 months | Level 3 | Derivative financial instruments      
Contingent consideration      
Change in fair value based on change in variable (215)    
Increasing the POS for the first milestone by 20% | Level 3 | Derivative financial instruments      
Contingent consideration      
Change in fair value based on change in variable 1,224    
Decreasing the POS for the first milestone by 20% | Level 3 | Derivative financial instruments      
Contingent consideration      
Change in fair value based on change in variable (1,224)    
Reducing the discount rate from 12.0% to 2.0% | Level 3 | Derivative financial instruments      
Contingent consideration      
Change in fair value based on change in variable 1,317    
Increasing the discount rate from 12.0% to 22.0% | Level 3 | Derivative financial instruments      
Contingent consideration      
Change in fair value based on change in variable $ (655)