CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Mar. 31, 2018	Dec. 31, 2017
Current assets
Cash and cash equivalents	$ 140,822	$ 159,371
Accounts receivable and accrued income from related party	1,057	1,586
Prepaid expenses	1,988	1,139
Other current assets	1,603	687
Total current assets	145,470	162,783
Non-current assets
Property, plant and equipment, net	33,839	34,281
Intangible assets, net	9,884	9,570
Goodwill	545	530
Restricted cash	2,500	2,480
Total non-current assets	46,768	46,861
Total assets	192,238	209,644
Current liabilities
Accounts payable	3,695	2,908
Accrued expenses and other current liabilities	6,491	8,838
Current portion of long-term debt	4,444	1,050
Current portion of deferred rent	1,086	737
Current portion of deferred revenue	9,696	4,613
Current portion of contingent consideration	1,145	1,084
Total current liabilities	26,557	19,230
Non-current liabilities
Long-term debt, net of current portion	16,369	19,741
Deferred rent, net of current portion	8,966	9,114
Deferred revenue, net of current portion	36,154	67,408
Contingent consideration, net of current portion	2,875	2,880
Derivative financial instruments related party	504	1,298
Other non-current liabilities	550	614
Total non-current liabilities	65,418	101,055
Total liabilities	91,975	120,285
Commitments and contingencies
Shareholders' equity
Ordinary shares, €0.05 par value: 60,000,000 shares authorized at March 31, 2018 and December 31, 2017 and 31,771,816 and 31,339,040 ordinary shares issued and outstanding at March 31, 2018 and December 31, 2017, respectively.	1,971	1,947
Additional paid-in-capital	570,595	566,530
Accumulated other comprehensive loss	(1,312)	(3,800)
Accumulated deficit	(470,991)	(475,318)
Total shareholders' equity	100,263	89,359
Total liabilities and shareholders' equity	$ 192,238	$ 209,644