X0508 4 2026-01-09 0 0001590560 uniQure N.V. QURE 0001376099 Kaye Jack C/O UNIQURE N.V. PAASHEUVELWEG 25A AMSTERDAM P7 11058BP NETHERLANDS 1 0 0 0 1 Ordinary Shares 2026-01-09 4 M 0 6390 19.39 A 26829 D Ordinary Shares 2026-01-09 4 S 0 6390 27.28 D 20439 D Stock Option (Right to Buy) 19.39 2026-01-09 4 M 0 6390 0 D 2028-01-26 Ordinary Shares 6390 0 D The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on June 16, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934. The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $27.19 to $27.39. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The Stock Option vested in full on January 26, 2019. /s/ Christian Klemt, Attorney-in-Fact 2026-01-12