X0306 4 2020-01-27 0001590560 uniQure N.V. QURE 0001716268 Gut Robert C/O UNIQURE N.V. PAASHEUVELWEG 25A AMSTERDAM P7 1105BP NETHERLANDS 0 1 0 0 Chief Medical Officer Ordinary Shares 2020-01-27 4 S 0 6897 60.01 D 28481 D Ordinary Shares 2020-01-28 4 S 0 596 62.19 D 27885 D The shares were sold pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934. As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. /s/ Christian Klemt, Attorney-in-Fact 2020-01-29