X0306 4 2023-02-27 0 0001590560 uniQure N.V. QURE 0001555508 Balachandran Madhavan C/O UNIQURE N.V. PAASHEUVELWEG 25A AMSTERDAM P7 11058BP NETHERLANDS 1 0 0 0 Ordinary Shares 2023-02-27 4 S 0 384 19.99 D 19573 D As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. /s/ Christian Klemt, Attorney-in-Fact 2023-03-01