<SEC-DOCUMENT>0001104659-20-127366-index.html : 20201119
<SEC-HEADER>0001104659-20-127366.hdr.sgml : 20201119
<ACCEPTANCE-DATETIME>20201119162726
ACCESSION NUMBER:		0001104659-20-127366
CONFORMED SUBMISSION TYPE:	SC 13D/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20201119
DATE AS OF CHANGE:		20201119
GROUP MEMBERS:		5AM CO-INVESTORS IV, L.P.
GROUP MEMBERS:		5AM OPPORTUNITIES I (GP), LLC
GROUP MEMBERS:		5AM OPPORTUNITIES I, L.P.
GROUP MEMBERS:		5AM PARTNERS IV, LLC
GROUP MEMBERS:		ANDREW J. SCHWAB
GROUP MEMBERS:		DR. JOHN D. DIEKMAN
GROUP MEMBERS:		DR. SCOTT M. ROCKLAGE

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Aprea Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001781983
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-91159
		FILM NUMBER:		201329097

	BUSINESS ADDRESS:	
		STREET 1:		535 BOYLSTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
		BUSINESS PHONE:		6095104718

	MAIL ADDRESS:	
		STREET 1:		535 BOYLSTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			5AM Ventures IV, L.P.
		CENTRAL INDEX KEY:			0001589315
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A

	BUSINESS ADDRESS:	
		STREET 1:		2200 SAND HILL ROAD, SUITE 110
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025
		BUSINESS PHONE:		650-233-8600

	MAIL ADDRESS:	
		STREET 1:		2200 SAND HILL ROAD, SUITE 110
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13D/A
<SEQUENCE>1
<FILENAME>a20-36446_1sc13da.htm
<DESCRIPTION>SC 13D/A
<TEXT>
Document 1 - file: a20-36446_1sc13da.htm

</DOCUMENT>
</SEC-DOCUMENT>