Stockholders’ Equity or Deficit (Tables)

9 Months Ended

Sep. 30, 2022

Equity [Abstract]

Summary of Capital Raises Since its Initial Public Offreing

The following table presents the Company’s capital raises since its initial public offering in March 2014:

	Date or period	Shares of common stock issued		Gross proceeds		Offering expenses			Net proceeds
Initial public offering	March 12, 2014		4,312,500	$	34,500	$	(4,244	)	$	30,256
Private placement	July 7, 2015		1,379,311		16,000		(1,188	)		14,812
Underwritten public offering	August 19, 2016		1,986,666		14,900		(1,533	)		13,367
Underwritten public offering	December 16, 2016		6,670,000		40,020		(3,132	)		36,888
2018 common stock purchase agreement with Aspire Capital	Year ended December 31, 2018		1,950,000		16,999		—			16,999
2019 common stock purchase agreement with Aspire Capital	Fourth quarter 2020		4,690,972		11,172		(78	)		11,094
Share issuance agreement for amendment 5 to Credit Agreement	February 2021		2,202,420		9,338		(20	)		9,318
Underwritten public offering	May 12, 2021		15,333,332		34,500		(2,397	)		32,103
Issuance of shares for IriSys acquisition	February 2022		9,302,718		20,931		(619	)		20,312