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Warrants - Additional Information (Details) - USD ($)
1 Months Ended 12 Months Ended
Aug. 15, 2016
Sep. 30, 2018
Dec. 31, 2019
Dec. 31, 2018
Sep. 25, 2018
Jun. 30, 2015
Jun. 30, 2014
Class of Stock [Line Items]              
Common stock warrants issued (in shares)       1      
Common stock, shares issued (in shares)   75,000 23,503,214 11,973,039      
Common stock warrant exercise price (in USD per share)   $ 3.5928          
Proceeds from issuance of warrants   $ 243,000          
Warrants outstanding (in shares)     274,524 274,524      
Hercules - June 2014              
Class of Stock [Line Items]              
Warrants outstanding (in shares)     1,583 1,583      
Exercise price (in USD per share)     $ 176.8     $ 147.4  
Warrants to purchase common stock (in shares)           2,035  
Hercules - June 2015              
Class of Stock [Line Items]              
Warrants outstanding (in shares)     2,035 2,035      
Exercise price (in USD per share)     $ 147.4        
Hercules - June 2015 | Amended Hercules Secured Term Loan              
Class of Stock [Line Items]              
Common stock warrants issued (in shares)             1,583
Exercise price (in USD per share)             $ 176.8
Private Investment in Public Equity (PIPE)              
Class of Stock [Line Items]              
Common stock warrants issued (in shares) 1            
Proceeds from issuance of common stock and warrants $ 7,500,000            
Costs related to offering $ 900,000            
Common stock shares issued (in shares) 239,997            
Offering price (in USD per share) $ 26.4            
Warrants outstanding (in shares) 480,000   195,906        
Warrant issuance price (in USD per share) $ 2.5            
Private Investment in Public Equity (PIPE) | Directors and Executive Officers              
Class of Stock [Line Items]              
Common stock shares issued (in shares) 13,771            
Warrants outstanding (in shares) 27,542            
Private Investment in Public Equity (PIPE) | Series B              
Class of Stock [Line Items]              
Warrants outstanding (in shares)     195,906 195,906      
Exercise price (in USD per share)     $ 31        
Private Investment in Public Equity (PIPE) | Warrants to purchase common stock | Series A              
Class of Stock [Line Items]              
Warrants outstanding (in shares) 239,997            
Private Investment in Public Equity (PIPE) | Warrants to purchase common stock | Series B              
Class of Stock [Line Items]              
Warrants outstanding (in shares) 239,997            
Exercise price (in USD per share) $ 31            
Trinity Capital Fund III, L.P.              
Class of Stock [Line Items]              
Debt instrument term     3 months        
Trinity Capital Fund III, L.P. | Build to Suit Obligation              
Class of Stock [Line Items]              
Line of credit     $ 14,000,000   $ 5,000,000    
Debt instrument term   36 months 36 months