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STATEMENTS OF CHANGES IN STOCKHOLDERS’ EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Loss
Public Stock Offering
Public Stock Offering
Common Stock
Public Stock Offering
Additional Paid-In Capital
At-The-Market Offering
At-The-Market Offering
Common Stock
At-The-Market Offering
Additional Paid-In Capital
Registered Direct Offering
Registered Direct Offering
Common Stock
Registered Direct Offering
Additional Paid-In Capital
Beginning balance (in shares) at Dec. 31, 2017   1,973,039                        
Beginning balance at Dec. 31, 2017 $ 7,048 $ 0 $ 232,922 $ (225,874) $ 0                  
Increase (Decrease) in Stockholders' Equity [Roll Forward]                            
Issuance of common stock in connection with offering, net (in shares)   10,000,000                        
Issuance of common stock in connection with offering, net 45,604 $ 1 45,603                      
Issuance of common stock warrants in connection with build-to-suit obligation 243   243                      
Stock-based compensation 1,178   1,178                      
Unrealized gain (loss) on marketable securities (5)       (5)                  
Net loss $ (35,358)     (35,358)                    
Ending balance (in shares) at Dec. 31, 2018 11,973,039 11,973,039                        
Ending balance at Dec. 31, 2018 $ 18,710 $ 1 279,946 (261,232) (5)                  
Increase (Decrease) in Stockholders' Equity [Roll Forward]                            
Issuance of common stock in connection with offering, net (in shares)             5,750,000     3,599,141     2,181,034  
Issuance of common stock in connection with offering, net           $ 18,331 $ 1 $ 18,330 $ 5,233   $ 5,233 $ 3,090   $ 3,090
Stock-based compensation 1,612   1,612                      
Unrealized gain (loss) on marketable securities 5       5                  
Net loss $ (37,589)     (37,589)                    
Ending balance (in shares) at Dec. 31, 2019 23,503,214 23,503,214                        
Ending balance at Dec. 31, 2019 $ 9,392 $ 2 $ 308,211 $ (298,821) $ 0