0000935836-24-000682.txt : 20241114 0000935836-24-000682.hdr.sgml : 20241114 20241114111634 ACCESSION NUMBER: 0000935836-24-000682 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20240930 FILED AS OF DATE: 20241114 DATE AS OF CHANGE: 20241114 EFFECTIVENESS DATE: 20241114 FILER: COMPANY DATA: COMPANY CONFORMED NAME: EcoR1 Capital, LLC CENTRAL INDEX KEY: 0001587114 ORGANIZATION NAME: IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-16764 FILM NUMBER: 241458705 BUSINESS ADDRESS: STREET 1: 357 TEHAMA STREET #3 CITY: SAN FRANCISCO STATE: CA ZIP: 94103 BUSINESS PHONE: 415-448-6534 MAIL ADDRESS: STREET 1: 357 TEHAMA STREET #3 CITY: SAN FRANCISCO STATE: CA ZIP: 94103 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false false false 0001587114 XXXXXXXX 09-30-2024 09-30-2024 false EcoR1 Capital, LLC

357 Tehama Street #3 San Francisco CA 94103

13F HOLDINGS REPORT 028-16764 000167121 801-100470 N Oleg Nodelman 415-448-6534 Oleg Nodelman San Francisco CA 11-13-2024 0 64 2921575681 INFORMATION TABLE 2 infotable.xml AADI BIOSCIENCE INC COM 00032Q104 3801221 1845253 SH SOLE 1845253 0 0 ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 26044828 27404070 SH SOLE 27404070 0 0 ALIGOS THERAPEUTICS INC COM NEW ADDED 01626L204 2213262 255573 SH SOLE 255573 0 0 ALLAKOS INC COM 01671P100 125640 192346 SH SOLE 192346 0 0 ALLOVIR INC COM 019818103 9131672 11294585 SH SOLE 11294585 0 0 ANAPTYSBIO INC COM 032724106 261132366 7794996 SH SOLE 7794996 0 0 APELLIS PHARMACEUTICALS INC COM 03753U106 342931912 11890843 SH SOLE 11890843 0 0 ARTIVA BIOTHERAPEUTICS INC COM ADDED 04317A107 640449 41453 SH SOLE 41453 0 0 ARVINAS INC COM 04335A105 165673473 6726491 SH SOLE 6726491 0 0 ATARA BIOTHERAPEUTICS INC COM NEW 046513206 3812466 468938 SH SOLE 468938 0 0 ATEA PHARMACEUTICALS INC COM 04683R106 18230352 5441896 SH SOLE 5441896 0 0 AVIDITY BIOSCIENCES INC COM 05370A108 34795466 757576 SH SOLE 757576 0 0 BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 20593300 910000 SH SOLE 910000 0 0 BRIDGEBIO PHARMA INC COM 10806X102 4332579 170172 SH SOLE 170172 0 0 CAREMAX INC *W EXP 06/08/202 14171W111 170000 100000 SH SOLE 100000 0 0 CARGO THERAPEUTICS INC COM 14179K101 27121500 1470000 SH SOLE 1470000 0 0 CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 22093500 650000 SH SOLE 650000 0 0 CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 51549377 3223851 SH SOLE 3223851 0 0 CRINETICS PHARMACEUTICALS IN COM 22663K107 219122932 4288120 SH SOLE 4288120 0 0 CRISPR THERAPEUTICS AG NAMEN AKT H17182108 65268186 1389276 SH SOLE 1389276 0 0 DAY ONE BIOPHARMACEUTICALS I COM 23954D109 12008607 862068 SH SOLE 862068 0 0 DESIGN THERAPEUTICS INC COM 25056L103 289627 53834 SH SOLE 53834 0 0 DYNE THERAPEUTICS INC COM 26818M108 19958732 555644 SH SOLE 555644 0 0 EDGEWISE THERAPEUTICS INC COM 28036F105 33372776 1250385 SH SOLE 1250385 0 0 ETON PHARMACEUTICALS INC COM 29772L108 3396450 566075 SH SOLE 566075 0 0 ETON PHARMACEUTICALS INC COM 29772L108 1368000 228000 SH Call SOLE 228000 0 0 GALAPAGOS NV SPON ADR 36315X101 4462623 155006 SH SOLE 155006 0 0 GENERATION BIO CO COM 37148K100 5055761 2046867 SH SOLE 2046867 0 0 HOOKIPA PHARMA INC COM NEW ADDED 43906K209 2458426 571727 SH SOLE 571727 0 0 IMMUNOME INC COM 45257U108 56717047 3879415 SH SOLE 3879415 0 0 IONIS PHARMACEUTICALS INC COM 462222100 20030000 500000 SH SOLE 500000 0 0 ITEOS THERAPEUTICS INC COM 46565G104 16423969 1608616 SH SOLE 1608616 0 0 JANUX THERAPEUTICS INC COM 47103J105 66773832 1469818 SH SOLE 1469818 0 0 JAZZ PHARMACEUTICALS PLC SHS USD G50871105 190117711 1706469 SH SOLE 1706469 0 0 KEROS THERAPEUTICS INC COM 492327101 10888125 187500 SH SOLE 187500 0 0 KURA ONCOLOGY INC COM 50127T109 113466259 5806871 SH SOLE 5806871 0 0 KYVERNA THERAPEUTICS INC COM 501976104 2200500 450000 SH SOLE 450000 0 0 LENZ THERAPEUTICS INC COM 52635N103 8232367 346772 SH SOLE 346772 0 0 MACROGENICS INC COM 556099109 184299 56018 SH SOLE 56018 0 0 MADRIGAL PHARMACEUTICALS INC COM 558868105 15916500 75000 SH SOLE 75000 0 0 MBX BIOSCIENCES INC COM ADDED 55287L101 30547518 1175809 SH SOLE 1175809 0 0 MERSANA THERAPEUTICS INC COM 59045L106 36599260 19364688 SH SOLE 19364688 0 0 NEUMORA THERAPEUTICS INC. COM 640979100 27363855 2071450 SH SOLE 2071450 0 0 NEUROGENE INC COM 64135M105 53345510 1271342 SH SOLE 1271342 0 0 NUVATION BIO INC *W EXP 07/07/202 67080N119 2206033 963333 SH SOLE 963333 0 0 NUVATION BIO INC COM CL A 67080N101 43990082 19209643 SH SOLE 19209643 0 0 ORIC PHARMACEUTICALS INC COM 68622P109 35035197 3418068 SH SOLE 3418068 0 0 PHARVARIS N V COM N69605108 16668000 900000 SH SOLE 900000 0 0 PRIME MEDICINE INC COM 74168J101 2709000 700000 SH SOLE 700000 0 0 PROQR THRAPEUTICS N V SHS EURO N71542109 3341504 1835991 SH SOLE 1835991 0 0 PROTHENA CORP PLC SHS G72800108 193805004 11584280 SH SOLE 11584280 0 0 RELAY THERAPEUTICS INC COM 75943R102 17700000 2500000 SH SOLE 2500000 0 0 REPLIMUNE GROUP INC COM 76029N106 9319737 850341 SH SOLE 850341 0 0 SURROZEN INC *W EXP 08/01/203 86889P117 798647 66665 SH SOLE 66665 0 0 TANGO THERAPEUTICS INC COM 87583X109 102646667 13330736 SH SOLE 13330736 0 0 TECTONIC THERAPEUTIC INC COM 878972108 25729033 849143 SH SOLE 849143 0 0 THIRD HARMONIC BIO INC COM 88427A107 43122116 3182444 SH SOLE 3182444 0 0 TSCAN THERAPEUTICS INC COM 89854M101 24900000 5000000 SH SOLE 5000000 0 0 VAXCYTE INC COM 92243G108 40276061 352464 SH SOLE 352464 0 0 VERVE THERAPEUTICS INC COM 92539P101 6050000 1250000 SH SOLE 1250000 0 0 VIRIDIAN THERAPEUTICS INC COM 92790C104 44563769 1958847 SH SOLE 1958847 0 0 VOYAGER THERAPEUTICS INC COM 92915B106 22917644 3917546 SH SOLE 3917546 0 0 XENCOR INC COM 98401F105 107194666 5330416 SH SOLE 5330416 0 0 ZYMEWORKS INC COM 98985Y108 168640286 13437473 SH SOLE 13437473 0 0