Note 5 - Property and Equipment, Net - Summary of Property and Equipment (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Property and equipment, gross	$ 17,516	$ 14,038
Less accumulated depreciation	(9,723)	(7,754)
Property and equipment, net	7,793	6,284
Laboratory Equipment [Member]
Property and equipment, gross	5,971	4,865
Leasehold Improvements [Member]
Property and equipment, gross	3,199	2,783
Office Equipment Furniture and Fixtures [Member]
Property and equipment, gross	3,364	2,841
Software and Software Development Costs [Member]
Property and equipment, gross	1,479	1,172
Specialized Shipping Containers [Member]
Property and equipment, gross	2,655	2,177
Construction in Progress [Member]
Property and equipment, gross	$ 848	$ 200

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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