Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Current assets:
Cash and cash equivalents	$ 59,110	$ 83,715
Accounts receivable, net	13,265	7,058
Inventory, net	7,437	7,099
Prepaid expenses and other	2,390	3,592
Total current assets	82,202	101,464
Restricted cash, non-current	200	80
Property and equipment, net	7,793	6,284
In-process research and development	16,170	1,782
Goodwill	3,822	45
Other intangible assets, net	11,017	179
Other assets	2,808	18
Total assets	124,012	109,852
Current liabilities:
Accounts payable	3,201	3,799
Accrued liabilities	14,282	9,949
Contingent purchase price consideration	882
Deferred income	41	1,654
Current portion of loans payable	84	79
Total current liabilities	18,490	15,481
Long-term portion of loans payable	29,601	386
Contingent purchase price consideration	2,593	1,293
Other liabilities	364
Total liabilities	51,048	17,160
Commitments and contingencies (Note 15)
Shareholders' equity:
Ordinary shares, £0.006705 nominal value; 36,183,293 shares authorized at December 31, 2016 and 2015, 22,635,431 and 22,549,488 shares issued and outstanding at December 31, 2016 and 2015, respectively	243	243
Additional paid-in capital	249,128	244,033
Accumulated deficit	(168,656)	(146,307)
Accumulated other comprehensive loss	(7,751)	(5,277)
Total shareholders’ equity	72,964	92,692
Total liabilities and shareholders’ equity	$ 124,012	$ 109,852