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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Cash flows from operating activities    
Net loss $ (18,088) $ (15,482)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,533 $ 1,239
Intangible asset impairment charge 385
Share-based compensation expense 2,582 $ 1,759
Change in fair value of contingent purchase price consideration $ 148 38
Loss on change in fair value of warrants 22
Changes in operating assets and liabilities, net of acquisition:    
Accounts receivable, net $ (721) (480)
Inventory (162) (1,112)
Prepaid expenses and other assets 12 115
Accounts payable 770 290
Accrued liabilities 922 (751)
Deferred income (258) 191
Net cash used in operating activities (12,877) (14,171)
Cash flows from investing activities    
Purchases of property and equipment (2,466) (2,567)
Purchases of intangible assets $ (45) (17)
Cash paid for acquisition, net of cash acquired (1,716)
Decrease in restricted cash $ 200 57
Net cash used in investing activities (2,311) $ (4,243)
Cash flows from financing activities    
Proceeds from issuance of ordinary shares 53,762
Proceeds from exercise of share options and warrants 14 $ 13
Payments on loan (107) (139)
Net cash provided by (used in) financing activities 53,669 (126)
Effect of exchange rate changes on cash and cash equivalents (163) 53
Net increase (decrease) in cash and cash equivalents, excluding restricted cash 38,318 (18,487)
Cash and cash equivalents at beginning of period 50,165 76,494
Cash and cash equivalents at end of period $ 88,483 58,007
Noncash investing and financing activities:    
Warrants liability reclassified to additional paid-in capital upon exercise of warrants $ 318