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Condensed Consolidated Balance Sheets (Unaudited) (USD $)
In Thousands, unless otherwise specified
Mar. 31, 2015
Dec. 31, 2014
Mar. 31, 2014
Current assets:      
Cash and cash equivalents $ 94,027us-gaap_CashAndCashEquivalentsAtCarryingValue $ 50,165us-gaap_CashAndCashEquivalentsAtCarryingValue $ 67,630us-gaap_CashAndCashEquivalentsAtCarryingValue
Restricted cash   200us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue  
Accounts receivable, net 7,234us-gaap_AccountsReceivableNetCurrent 6,823us-gaap_AccountsReceivableNetCurrent  
Inventory 5,757us-gaap_InventoryNet 6,425us-gaap_InventoryNet  
Prepaid expenses and other assets 4,398us-gaap_PrepaidExpenseAndOtherAssetsCurrent 2,755us-gaap_PrepaidExpenseAndOtherAssetsCurrent  
Total current assets 111,416us-gaap_AssetsCurrent 66,368us-gaap_AssetsCurrent  
Restricted cash, non-current 192us-gaap_RestrictedCashAndCashEquivalentsNoncurrent 192us-gaap_RestrictedCashAndCashEquivalentsNoncurrent  
Property and equipment, net 5,123us-gaap_PropertyPlantAndEquipmentNet 4,537us-gaap_PropertyPlantAndEquipmentNet  
In-process research and development 2,128us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill 2,399us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill  
Goodwill 44us-gaap_Goodwill 50us-gaap_Goodwill  
Other intangible assets, net 250us-gaap_IntangibleAssetsNetExcludingGoodwill 273us-gaap_IntangibleAssetsNetExcludingGoodwill  
Other assets 24us-gaap_OtherAssetsNoncurrent 30us-gaap_OtherAssetsNoncurrent  
Total assets 119,177us-gaap_Assets 73,849us-gaap_Assets  
Current liabilities:      
Accounts payable 2,695us-gaap_AccountsPayableCurrent 2,368us-gaap_AccountsPayableCurrent  
Accrued liabilities 4,622us-gaap_AccruedLiabilitiesCurrent 7,070us-gaap_AccruedLiabilitiesCurrent  
Deferred income 1,886us-gaap_DeferredRevenueCurrent 1,993us-gaap_DeferredRevenueCurrent  
Current portion of loans payable 131us-gaap_LoansPayableCurrent 137us-gaap_LoansPayableCurrent  
Total current liabilities 9,334us-gaap_LiabilitiesCurrent 11,568us-gaap_LiabilitiesCurrent  
Long-term portion of loans payable 418us-gaap_LongTermLoansPayable 454us-gaap_LongTermLoansPayable  
Contingent purchase price consideration 1,126us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent 1,218us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent  
Total liabilities 10,878us-gaap_Liabilities 13,240us-gaap_Liabilities  
Commitments and contingencies (Note 2)       
Shareholders’ equity:      
Ordinary shares, £0.006705 nominal value; 36,183,293 shares authorized at March 31, 2015 and December 31, 2014, and 22,513,782 and 17,614,650 shares issued and outstanding at March 31, 2015 and December 31, 2014, respectively 242us-gaap_CommonStockValue 192us-gaap_CommonStockValue  
Additional paid-in capital 241,416us-gaap_AdditionalPaidInCapital 186,816us-gaap_AdditionalPaidInCapital  
Accumulated deficit (128,140)us-gaap_RetainedEarningsAccumulatedDeficit (121,829)us-gaap_RetainedEarningsAccumulatedDeficit  
Accumulated other comprehensive loss (5,219)us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax (4,570)us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax  
Total shareholders’ equity 108,299us-gaap_StockholdersEquity 60,609us-gaap_StockholdersEquity  
Total liabilities and shareholders’ equity $ 119,177us-gaap_LiabilitiesAndStockholdersEquity $ 73,849us-gaap_LiabilitiesAndStockholdersEquity