Subsequent Events (Details)																				3 Months Ended	12 Months Ended
	Mar. 19, 2024 shares	Mar. 18, 2024 USD ($) $ / shares shares	Mar. 05, 2024 shares	Feb. 29, 2024 shares	Feb. 27, 2024 shares	Jan. 29, 2024 USD ($) shares	Jan. 15, 2024 shares	Dec. 28, 2023 USD ($) shares	Sep. 29, 2023 shares	Mar. 23, 2023 shares	Mar. 17, 2023 shares	Nov. 18, 2022 shares	Jul. 25, 2022 shares	May 13, 2022 shares	Mar. 09, 2022 shares	Mar. 04, 2022 shares	Mar. 02, 2022 shares	Feb. 11, 2022 shares	Apr. 13, 2021 shares	Apr. 01, 2024 USD ($) shares	Dec. 31, 2023 USD ($) shares	Mar. 01, 2024 shares
Iliad
Subsequent Events.
Issuance of common stock (In shares)								4,875,000		3,733	14,533	73,333	31,546	15,249	24,667	26,667	32,333	23,117	7,843
Iliad | October 2020 royalty interest agreements
Subsequent Events.
Aggregate shares value | $								$ 789,000
December 2021 ATM Agreement
Subsequent Events.
Issuance of common stock (In shares)																					55,222,809
Proceeds from issuance of Common stock | $																					$ 56,100,000
Series I convertible preferred stock
Subsequent Events.
Issuance of common stock (In shares)									118
Subsequent event
Subsequent Events.
PIPE warrant exchange ratio					0.4
Shares issued on conversion on common stock	8,333,333
Subsequent event | Securities Purchase Agreement
Subsequent Events.
Shares Issued, Price Per Share | $ / shares		$ 0.12
Subsequent event | Iliad | October 2020 royalty interest agreements
Subsequent Events.
Issuance of common stock (In shares)						8,000,000
Aggregate shares value | $						$ 900,800
Subsequent event | Streeterville
Subsequent Events.
Shares issued on conversion on common stock			10,000,000
Subsequent event | Streeterville | August 2022 Purchase Agreement
Subsequent Events.
Issuance of common stock (In shares)						1,587,632
Aggregate shares value | $						$ 179,000
Subsequent event | Gen Ilac Ve Saglik Urunleri Sanayi Ve Ticaret, A.S | Securities Purchase Agreement
Subsequent Events.
Issuance of common stock (In shares)		16,666,666
Proceeds from issuance of Common stock | $		$ 2,000,000.0
Subsequent event | December 2021 ATM Agreement
Subsequent Events.
Number of shares issued																				133,631,424
Total net proceeds | $																				$ 11,600,000
Subsequent event | Series I convertible preferred stock
Subsequent Events.
Shares converted							56
Subsequent event | Series J convertible preferred stock
Subsequent Events.
Shares converted	40
Subsequent event | Series J convertible preferred stock | Streeterville
Subsequent Events.
Preferred stock, shares issued																						179.3822
Shares converted			40
Subsequent event | Series G Preferred Stock
Subsequent Events.
Shares converted				122
Subsequent event | Common Stock
Subsequent Events.
Number of shares issued for convertible preferred stock							2,696,456
Shares issued on conversion on common stock				3,050,000	18,837,500
Subsequent event | PIPE Warrants
Subsequent Events.
Shares converted					7,535,000